Uremia Symptoms

Uremia is a severe stage of end-stage chronic kidney disease, where the kidney function significantly declines, causing the accumulation of metabolic waste in the body. This disease is commonly seen in patients with various forms of chronic nephritis, hypertensive nephropathy, and diabetic nephropathy. Globally, the incidence of uremia is increasing with aging and the rise in chronic diseases, and patient management is more developed in European and American countries.

In Southeast Asia, countries like China, India, and Vietnam have seen a yearly increase in the number of uremic patients. The lack of medical resources and early diagnosis has exacerbated the condition, severely affecting the quality of life of patients.

Detailed Symptoms of Uremia

1. Abnormal Urination
In the early stages of uremia, patients may experience a decrease in urine output or complete absence of urine, with urine becoming cloudy or bloody, reflecting severe impairment of kidney excretory function.

2. Fatigue and Weight Loss
Patients often feel generalized weakness and weight loss due to metabolic disturbances and impaired nutrient absorption, which affects overall health.

3. Nausea and Vomiting
Toxins accumulating in the body stimulate the digestive system, causing frequent nausea, vomiting, and a significant decrease in appetite.

4. Edema
The retention of salt and water in the body leads to swelling in the lower limbs, face, and throughout the body. In severe cases, this may cause difficulty breathing.

5. Anemia Symptoms
Due to insufficient erythropoietin from the kidneys, patients commonly exhibit pale skin, dizziness, and fatigue, affecting physical endurance.

6. Neurological Symptoms
These include headaches, insomnia, poor concentration, and numbness in the hands and feet. In severe cases, patients may experience confusion or even coma.

7. Cardiovascular Issues
Patients with uremia often have high blood pressure and arrhythmias. Some may develop heart failure or chest pain, which can be life-threatening.

8. Skin Changes
Skin becomes dry and itchy, with possible jaundice, due to the impact of toxins on skin metabolism.

9. Bone Disorders
Bone pain and osteoporosis are common complications of uremia, affecting patients' mobility and quality of life.

Conclusion

The symptoms of uremia are diverse and affect multiple systems. The condition is severe and progresses rapidly. Without timely treatment, the patient's quality of life dramatically declines, and it can even be life-threatening. Experts from Life International Medical Center emphasize that early identification and comprehensive therapies, including stem cell treatments, are crucial for improving the prognosis of uremic patients. There is a call to strengthen disease management and ongoing treatment.