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Chronic nephritis refers to persistent inflammation of the glomeruli and renal interstitium caused by various factors, leading to irreversible kidney damage. Ultimately, it may develop into chronic renal failure or even uremia, seriously threatening life and health. This disease can occur in individuals of all ages, and its causes are complex, including infections, autoimmune abnormalities, and more. Treatment focuses on early diagnosis, early intervention, maintaining kidney function, and slowing disease progression.
The prevalence of chronic nephritis is relatively stable in Europe and America, influenced largely by lifestyle and healthcare conditions. In these regions, early screening and treatment are prioritized, and patient management systems are well-established, resulting in relatively good disease control.
In Southeast Asia, the prevalence of chronic nephritis continues to rise due to imbalanced medical resources and environmental factors. In countries like China and India, the disease incidence has been increasing, and although chronic kidney disease prevention and treatment systems are gradually improving, challenges such as heavy patient burdens and poor treatment compliance remain.
1. Continuous Deterioration of Kidney Function
Chronic inflammation damages the glomeruli, leading to a gradual decline in the glomerular filtration rate and weakened detoxification capacity, ultimately causing renal failure.
2. Increased Risk of Hypertension and Cardiovascular Disease
Kidney dysfunction causes water and salt metabolism disorders, leading to hypertension. Long-term hypertension adds strain on the heart and increases the risk of cardiovascular diseases.
3. Metabolic Disorders and Complications
Patients with chronic nephritis often experience anemia, electrolyte imbalances, and bone metabolism abnormalities, significantly impacting overall health across multiple body systems.
4. Progression to Uremia
If chronic nephritis is not effectively controlled, it can eventually progress to uremia, requiring dialysis or kidney transplantation to sustain life.
Stem Cell Therapy
Stem cell therapy has shown potential in regulating immune responses and promoting kidney tissue repair, offering hope for restoring kidney function in chronic nephritis patients.
① Promote regeneration of damaged kidney cells
② Suppress inflammation
③ Regulate immune balance
④ Alleviate renal interstitial fibrosis
⑤ Delay disease progression, offering a new direction in chronic nephritis treatment.
1. Medication Therapy
This mainly includes immunosuppressants, anti-inflammatory drugs, antihypertensive agents, and kidney-protective medications, aiming to control inflammation and protect kidney function, slowing disease progression.
2. Lifestyle Adjustments
A low-salt, low-protein diet, weight management, smoking cessation, alcohol limitation, and regular sleep patterns are important measures to reduce kidney burden and assist medication treatment.
3. Blood Pressure Management
Controlling blood pressure is key to preventing further kidney damage. ACE inhibitors or ARBs are commonly used to effectively protect glomerular function.
4. Complication Treatment
Comprehensive management of complications such as anemia, bone disease, and electrolyte disturbances can improve the overall health status of the patient.
Chronic nephritis severely affects kidney function and overall health, requiring early diagnosis and active treatment. Experts from the International Life Medical Center emphasize that combining stem cell therapy with comprehensive treatment plans can effectively delay disease progression and improve quality of life, urging patients to actively cooperate in treatment for scientific disease management.
