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Pulmonary fibrosis is a disease in which scarring forms after lung tissue damage, leading to decreased lung function. It is more common in middle-aged and elderly people, with causes including environmental factors, occupational exposure, genetics, and autoimmunity. Without timely treatment, the disease continues to worsen, seriously affecting quality of life and survival.
Europe and the United States
There are more pulmonary fibrosis patients in Western countries, especially among people over 60 years old. High levels of industrialization and smoking are the main risk factors, resulting in a significant disease burden and increasing healthcare resource investment.
Southeast Asia
In some Southeast Asian countries, pulmonary fibrosis incidence is gradually increasing due to environmental pollution and occupational exposure. With improved healthcare standards, awareness of early diagnosis and treatment has grown, and patient prognosis has improved.
1. Decline in Lung Function
Pulmonary fibrosis causes lung tissue hardening, reduced lung capacity, and impaired gas exchange. Patients gradually develop shortness of breath and reduced endurance, severely affecting daily life.
2. Chronic Hypoxia
Fibrosis obstructs oxygen entry into the bloodstream, leading to systemic hypoxia. Over time, this may result in increased cardiac load and pulmonary hypertension.
3. Reduced Quality of Life
Patients often experience fatigue, coughing, and dyspnea, which affect daily activities and mental health, causing significant lifestyle disruption.
4. Poor Prognosis
If not effectively controlled, pulmonary fibrosis can progress rapidly, eventually leading to respiratory failure and life-threatening conditions.
Stem Cell Therapy
Stem cell therapy repairs damaged lung tissue and modulates immune responses, effectively slowing fibrosis progression. Its advantages include: ① promoting tissue regeneration ② improving lung function ③ reducing inflammation ④ enhancing repair capacity ⑤ improving quality of life.
1. Antifibrotic Drugs
For idiopathic pulmonary fibrosis, drugs such as pirfenidone and nintedanib help inhibit the fibrotic process, slow lung function decline, and extend survival.
2. Oxygen Therapy
Provides continuous oxygen support for hypoxic patients, relieves symptoms, improves tissue oxygenation, and enhances comfort.
3. Pulmonary Rehabilitation
Through scientific exercise and rehabilitation training, patients can strengthen physical fitness and respiratory muscle function, improving breathing efficiency and alleviating symptoms.
4. Immunomodulatory Therapy
Some patients benefit from immunosuppressants to control abnormal immune responses, slowing disease progression, particularly for specific types of pulmonary fibrosis.
5. Supportive Therapy
Including nutritional support, psychological counseling, and symptomatic management, to help patients better cope with the disease.
6. Surgical Treatment
Lung transplantation offers a possible cure for patients with advanced pulmonary fibrosis, but its indications are limited and risks are high.
7. Acute Exacerbation Management
Promptly addressing acute exacerbations with steroids and anti-infective therapy helps prevent further deterioration.
8. Environmental Control
Avoiding occupational exposure and environmental pollution reduces lung damage risks and helps stabilize the condition.
Pulmonary fibrosis severely impairs respiratory function and quality of life. Early diagnosis and scientific treatment are essential. Experts from the United Life International Medical Center remind us that combining modern stem cell therapy with multidisciplinary treatment can effectively slow disease progression and improve patient outcomes. Patients should actively cooperate with treatment and maintain healthy lifestyle habits.
