Pulmonary fibrosis is a chronic lung disease mainly characterized by interstitial fibrosis of lung tissue, resulting in progressive lung function impairment. Without timely diagnosis and treatment at an early stage, the disease worsens and may even lead to respiratory failure, severely affecting quality of life. Diagnosing pulmonary fibrosis requires a combination of clinical presentation, imaging studies, and pulmonary function testing to scientifically evaluate the condition and guide treatment.
1. Imaging Examination
High-resolution CT is an important tool for diagnosing pulmonary fibrosis. Typical findings include thickened lung markings, honeycombing, and reticular shadows, which help determine the extent and severity of lesions.
2. Pulmonary Function Testing
Pulmonary function tests reveal ventilatory restriction, decreased lung volumes, and reduced diffusion capacity, reflecting the degree of fibrosis and impairment of respiratory function.
3. Blood Biomarkers
Elevated levels of serum KL-6, SP-D, and other markers suggest increased activity of pulmonary fibrosis and aid in monitoring the disease and assessing treatment effectiveness.
4. Pathological Examination
Lung tissue biopsy can provide a definitive diagnosis. Pathological features include alveolar wall thickening and interstitial fibrosis, sometimes accompanied by inflammatory cell infiltration.
5. Clinical Manifestations and Medical History
Chronic cough, progressive dyspnea, and a history of occupational exposure contribute to supporting the diagnosis.
6. Gas Exchange Function Testing
Arterial blood gas analysis often shows decreased oxygen partial pressure, indicating impaired pulmonary gas exchange function.
7. Other Auxiliary Examinations
Echocardiography and exercise testing are used to evaluate complications and the severity of the disease.
The key to diagnosing pulmonary fibrosis lies in early recognition and accurate assessment. Experts at the United Life International Medical Center emphasize that combining multiple diagnostic methods can effectively improve diagnostic accuracy. Timely diagnosis facilitates early intervention, slows disease progression, and improves quality of life. Both healthcare providers and patients should pay close attention to the early diagnosis and management of pulmonary fibrosis and actively cooperate with scientific treatment strategies.