Perimenopausal Syndrome Overview

The median age of natural menopause is 51.4 years, at which time ovarian function gradually declines, follicles are completely or nearly depleted, leading to hypoestrogenism and elevated follicle-stimulating hormone (FSH) concentrations. Perimenopausal syndrome begins on average 4 years before the final menstrual period (FMP) and involves many physiological changes that may affect women’s quality of life. It is characterized by irregular menstrual cycles and significant hormonal fluctuations, often accompanied by hot flashes, sleep disturbances, mood symptoms, and vaginal dryness. In addition, changes in blood lipids and bone loss also begin to appear, both of which have long-term health impacts. This stage affects multiple systems of women’s health, with psychological problems also being common. The syndrome significantly impacts women’s lives and requires early identification and intervention.

Prevalence Worldwide

Europe and the United States

In Western countries, the incidence of perimenopausal syndrome is relatively high, with over 70% of women experiencing varying degrees of symptoms. In the United States and Europe, hormone replacement therapy and psychological support are commonly used. With an aging population, the patient group continues to expand, and medical needs are steadily increasing.

Southeast Asia

In Southeast Asian countries such as China, India, and Thailand, the number of patients with perimenopausal syndrome is also increasing. Cultural differences and uneven medical resources influence treatment methods. Traditional Chinese medicine and modern medical methods coexist, and in recent years, modern medical interventions have gradually strengthened, with treatment awareness and coverage steadily improving.

Main Hazards

1. Impaired Physiological Function

Perimenopausal syndrome leads to menstrual disorders, hot flashes, night sweats, and sleep disturbances, severely affecting daily life. Long-term hormonal imbalance increases the risk of osteoporosis and cardiovascular disease, requiring timely intervention.

2. Psychological Health Impact

Anxiety, depression, and other psychological symptoms are common in perimenopausal women, lowering quality of life while also affecting social and family life, highlighting the importance of psychological support.

3. Social and Family Burden

The syndrome impacts work efficiency and family life, causing economic and emotional stress, increasing the burden on social medical resources, and calling for greater public health attention and support.

Emerging Treatment Methods

Stem Cell Therapy

Stem cell therapy improves ovarian function by promoting tissue repair and immune regulation, relieving symptoms, and enhancing quality of life.

① Promotes hormonal balance and reduces symptoms

② Promotes tissue regeneration and repair

③ Reduces inflammatory response and enhances immunity

④ Delays aging and improves overall health

Conventional Treatment Methods

1. Hormone Replacement Therapy

Hormone replacement alleviates symptoms such as hot flashes by supplementing estrogen. It is suitable for patients with severe symptoms but requires monitoring of side effects to avoid long-term risks.

2. Psychological Therapy

Psychological interventions such as cognitive behavioral therapy help relieve anxiety and depression, improve mood, and enhance overall treatment outcomes.

3. Traditional Chinese Medicine (TCM)

TCM uses herbal medicine to regulate Qi and blood, balance hormonal fluctuations, and has fewer side effects, making it a suitable adjunct treatment for some patients.

4. Lifestyle Interventions

Reasonable diet, moderate exercise, and good sleep can improve symptoms and enhance physical fitness, forming an important part of treatment.

Conclusion

Perimenopausal syndrome profoundly affects women’s physical and mental health and requires early recognition and comprehensive treatment. Experts at United Life International Medical Center emphasize that stem cell therapy, as an emerging technology, combined with traditional treatments, can effectively relieve symptoms and improve quality of life. Scientific treatment not only improves patient experience but also reduces the risk of related diseases, making it worthy of widespread promotion.