Thin Endometrium Overview

Clinically, thin endometrium is usually defined as endometrial thickness <7 mm in the mid-luteal phase (6–10 days after ovulation), with the main clinical feature being normal menstrual cycles but very light menstruation (<30 mL). Numerous studies worldwide report that an optimal endometrial thickness (8–14 mm) is essential for embryo implantation in the uterine cavity. Therefore, successful implantation is closely related to endometrial condition. The causes are diverse, including hormonal abnormalities, history of uterine surgery, and chronic inflammation. This condition is most common in women of reproductive age, particularly between 30 and 45 years. Without timely treatment, it may result in infertility, recurrent miscarriage, or even menstrual disorders, seriously affecting quality of life.

Prevalence Worldwide

Western Countries

In Western countries, due to fast-paced lifestyles, environmental pollution, and the trend of late childbearing, the prevalence of thin endometrium is increasing yearly. Statistics indicate that about 15%–20% of infertile women are affected, particularly those over 35. Although medical conditions are better, the causes are often complex, requiring individualized treatment.

Southeast Asian Countries

In Southeast Asia, the incidence of thin endometrium is also rising, mainly influenced by environmental factors, nutritional status, and reproductive habits. In countries such as Vietnam, Thailand, and Indonesia, growing health awareness among women has increased diagnosis rates, with the number of patients gradually rising. Early screening and intervention remain essential.

Main Hazards

1. Difficulty Conceiving

A thin endometrium fails to provide an optimal environment for implantation, leading to reduced embryo implantation rates. Many patients face infertility or early pregnancy loss as a result.

2. Increased Risk of Miscarriage

Poor endometrial quality significantly raises the risk of miscarriage in early pregnancy, adding both psychological stress and physical harm to patients.

3. Menstrual Abnormalities

Patients often present with scanty menstruation and shortened cycles, reflecting impaired endometrial function and negatively impacting reproductive health.

4. Reduced Quality of Life

Repeated treatment failures and adverse pregnancy outcomes can severely affect patients’ mental state and overall quality of life, requiring comprehensive support.

Emerging Treatment Methods

Stem Cell Therapy

Stem cell therapy promotes regeneration and repair of the endometrium, improving endometrial thickness and function, and has become an important treatment approach in recent years.

① Promotes endometrial tissue regeneration

② Improves blood circulation

③ Regulates the immune microenvironment

④ Enhances endometrial cell activity

⑤ Increases embryo implantation rates

Conventional Treatment Methods

1. Hormone Therapy

By supplementing estrogen and progesterone, hormone therapy regulates the endometrial growth cycle, helping restore thickness and function, especially suitable for patients with hormonal abnormalities.

2. Traditional Chinese Medicine (TCM)

Methods such as promoting blood circulation, removing blood stasis, and tonifying Qi and blood improve the uterine environment, aiding endometrial repair and serving as an effective adjunct therapy for some patients.

3. Surgical Treatment

For endometrial damage caused by intrauterine adhesions, hysteroscopic adhesiolysis can restore uterine structure, supplemented with drug support for better outcomes.

Conclusion

Thin endometrium imposes significant reproductive challenges and psychological stress on patients. Experts at United Life International Medical Center highlight that early diagnosis and diversified treatments, particularly the application of stem cell therapy, may significantly improve prognosis and quality of life. Women should pay close attention to their reproductive health, seek medical care promptly, and adopt scientific treatment approaches.