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Penile cancer is a rare tumor that occurs mostly in middle-aged and elderly men, characterized by rapid progression and heavy psychological burden. Most patients are over 50 years old, but some younger individuals may also be affected due to HPV infection or phimosis. Once diagnosed, treatment should begin as early as possible. Delays may result in tumor invasion into the urethra, pelvis, or metastasis to lymph nodes and even distant organs, seriously threatening life and quality of life.
Immune reconstruction cell therapy activates the patient’s own immune system to recognize and eliminate cancer cells, improving systemic and sustained treatment effects. It shows promising potential in controlling tumor recurrence and preventing distant metastasis, especially suitable for postoperative consolidation therapy or patients who cannot undergo surgery.
① Precisely identifies residual cancer cells, reducing recurrence rates.
② Enhances overall immune function, helping to prevent other cancers from occurring.
③ Suitable for combined use with radiotherapy or chemotherapy to enhance efficacy.
④ Has fewer side effects and less overall impact on the body, making it suitable for elderly or frail patients.
During actual treatment, cancer patients undergoing traditional approaches such as surgery, radiotherapy, or chemotherapy often face problems of immune dysfunction, increased infection risk, and slow recovery. To help patients better sustain treatment, improve tolerance, and enhance quality of life, it is necessary to scientifically design phased immune reconstruction plans tailored to different treatment cycles.
● Short-term plan: Rapidly enhance immunity through immune cell reinfusion to boost the effectiveness of anti-tumor treatment.
● Mid-term plan: Reduce side effects of traditional treatments, promote physical recovery, and complete standardized treatment courses.
● Long-term plan: Improve overall immunity through immune cell reconstruction, gut immune reconstruction, elemental immune reconstruction, and immune nutrition reconstruction, thereby improving quality of life and prolonging survival.
1. Traditional Surgical Resection
Surgical resection remains one of the main treatments for penile cancer. Depending on lesion size and depth of invasion, partial or total penectomy may be performed. For early localized lesions, part of the tissue can be preserved to maintain urinary and partial sexual function. Postoperative lymph node dissection may be considered based on whether metastasis has occurred.
2. Minimally Invasive Surgery and Laser Therapy
Minimally invasive surgical techniques such as carbon dioxide laser excision and electrocautery have matured in recent years, suitable for superficial lesions. Laser therapy can effectively remove tumors while preserving organs, with less trauma and faster recovery, particularly suitable for early-stage patients or those requiring functional preservation.
3. Radiotherapy
For patients who cannot undergo surgery or need postoperative local recurrence control, external beam radiotherapy is an option. It is especially suitable for elderly or frail patients, or those with postoperative recurrence and multiple comorbidities. However, the treatment course is long, and some may experience side effects such as skin burns or local inflammation.
4. Chemotherapy
Chemotherapy is often used in advanced or metastatic penile cancer patients, with common drugs including cisplatin and fluorouracil. Used alone or combined with immunotherapy, it can control tumor progression to some extent and relieve symptoms. However, systemic side effects such as nausea, hair loss, and immunosuppression must be considered.
5. Local Photodynamic Therapy (PDT)
Photodynamic therapy uses a combination of specific wavelength lasers and photosensitizing drugs to destroy tumor cells. This method is suitable for very early or carcinoma in situ lesions, offering organ preservation advantages with minimal trauma and fast recovery. However, it is currently mainly promoted in clinical trials.
6. Psychological and Rehabilitation Interventions
In addition to focusing on tumor control, psychological trauma in penile cancer patients must also be addressed. Loss of sexual function or organ removal after surgery can lead to severe self-denial. Therefore, psychological counseling, rehabilitation training, and sexual life guidance should be integrated into treatment plans to help patients rebuild self-esteem and improve quality of life.
Treatment of penile cancer is no longer limited to traditional resection. New technologies such as immune reconstruction cell therapy provide patients with more options. Experts at United Life International Medical Center point out that selecting individualized treatment plans based on tumor stage, functional preservation needs, and overall health condition is the key to improving survival rates and quality of life.
