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Oral cancer is a common malignant tumor of the head and neck, mainly affecting middle-aged and elderly people, especially those with smoking and drinking habits. The timing and method of treatment have a major impact on prognosis. Missing early treatment leads to rapid disease progression and increased risk of recurrence. The mainstream approach to managing oral cancer today is the combination of multiple treatment modalities.
Immune reconstruction cell therapy, as an emerging approach, can enhance the patient’s immune system to better recognize and kill cancer cells, thereby improving treatment outcomes. This therapy works by activating and proliferating specific immune cells to precisely target tumors, reducing the likelihood of recurrence.
① Activate T cells to enhance immune surveillance capacity.
② Boost the anti-tumor activity of natural killer cells.
③ Improve the immune microenvironment and inhibit tumor immune evasion.
In actual treatment, since cancer patients undergoing surgery, radiotherapy, and chemotherapy often experience impaired immune function, increased risk of infection, and slow recovery, it is necessary to formulate phased immune reconstruction plans across different treatment cycles to better support the treatment process, improve tolerance, and enhance survival quality.
● Short-term Plan: Rapidly enhance immunity through immune cell reinfusion, boosting the effectiveness of anti-cancer treatment.
● Mid-term Plan: Reduce side effects of traditional treatments, promote physical recovery, and complete standardized treatment courses.
● Long-term Plan: Enhance overall immunity through immune cell reconstruction, gut immune reconstruction, elemental immune reconstruction, and immune nutrition reconstruction, thereby improving quality of life and extending survival.
1. Surgical Treatment
Surgical resection is the preferred treatment for early and some intermediate cases of oral cancer. The goal is complete removal of the tumor and affected tissues to reduce the risk of local recurrence. Depending on tumor size and location, partial resection of oral structures may be necessary, and some patients may require cervical lymph node dissection.
2. Radiotherapy
Radiotherapy is suitable for patients who cannot undergo surgery, or as postoperative adjuvant therapy. It uses high-energy radiation to kill cancer cells and control local tumor progression. Modern techniques such as Intensity-Modulated Radiotherapy (IMRT) allow precise targeting, minimizing damage to surrounding normal tissues.
3. Chemotherapy
Chemotherapy is usually applied in advanced or metastatic oral cancer, either alone or combined with radiotherapy. Common drugs include cisplatin and fluorouracil, which can reduce tumor size and relieve symptoms, though side effects are significant.
4. Minimally Invasive Treatment Methods
In recent years, minimally invasive techniques have been increasingly applied in oral cancer treatment, including transoral endoscopic resection and laser therapy. These approaches cause less trauma, allow faster recovery, and are suitable for early localized lesions. Minimally invasive technology combined with radiotherapy and immunotherapy improves comprehensive treatment outcomes.
5. Cryoablation
A liquid nitrogen probe contacts the tumor, freezing and thawing at -196°C to destroy cells. This method is suitable for small, exophytic lesions (such as lip cancer) or elderly patients unfit for surgery. It is simple to perform but contraindicated for lesions near bone tissue (risk of necrosis).
6. Photodynamic Therapy
After intravenous injection of a photosensitizer, laser light guided by optical fibers is applied to the lesion. This selectively kills cancer cells and is used for treating carcinoma in situ, superficial squamous carcinoma, or precancerous lesions such as leukoplakia. It is non-invasive, but requires one month of light avoidance, and can be repeated.
7. Comprehensive Treatment Strategies
Depending on the stage and condition of the patient, multidisciplinary comprehensive treatment is often employed, combining surgery, radiotherapy, chemotherapy, and immunotherapy to improve success rates and prognosis. The design of individualized treatment plans is increasingly emphasized.
Experts at United Life International Medical Center emphasize that oral cancer treatment requires a combination of approaches. The inclusion of immune reconstruction cell therapy brings new hope for patients. Early diagnosis and treatment are key to improving cure rates, and patients should actively cooperate with physicians to develop appropriate treatment plans.
