Lymphoma Symptoms

Lymphoma is a malignant tumor originating from lymphatic tissues, mainly affecting lymph nodes, spleen, bone marrow, and other lymphoid organs. Globally, the incidence is higher in the United States, Europe, and some Asian countries. Non-Hodgkin lymphoma cases outnumber Hodgkin lymphoma, with males being slightly more affected than females. In Southeast Asian countries such as Singapore, Malaysia, and Thailand, incidence rates have been increasing in recent years, related to viral infections and environmental factors. Lymphoma significantly impacts immune function, and without timely treatment, the condition can deteriorate rapidly.

In Southeast Asia, the incidence of lymphoma is closely linked to infections such as the Epstein-Barr virus, particularly in immunocompromised individuals who are more susceptible. The disease poses a serious threat to patient health, with diverse clinical manifestations involving multiple body systems. Emerging immune reconstruction cell therapy has brought new treatment hope to lymphoma patients, improving prognosis for some.

Lymphoma Staging

Stage I: Involvement of a single lymph node region
The tumor is limited to a single lymph node region or a single organ, with relatively mild symptoms. Treatment outcomes are favorable at this stage, with a 5-year survival rate of about 80%-90%.

Stage II: Multiple lymph node regions on the same side
The tumor involves multiple lymph node regions on the same side, possibly with local symptoms. Treatment becomes more challenging, with a 5-year survival rate of about 60%-75%.

Stage III: Multiple lymph node regions on both sides
The tumor affects lymph node regions on both sides of the body, along with spleen involvement. Symptoms are more pronounced, and the 5-year survival rate drops to 40%-60%.

Stage IV: Extensive organ infiltration
The tumor invades bone marrow, liver, and other distant organs, presenting severe manifestations. The 5-year survival rate is less than 30%. Comprehensive treatment and immune reconstruction cell therapy are the main approaches.

Detailed Symptoms of Lymphoma

1. Lymph node enlargement
Painless lymph node enlargement is the most common early symptom of lymphoma, often occurring in the neck, armpits, and groin. The masses are firm and gradually increase in size.

2. Persistent fever and night sweats
Unexplained persistent fever and night sweats are typical B symptoms of lymphoma, reflecting abnormal immune responses.

3. Rapid weight loss
Patients often experience significant unexplained weight loss, indicating disease progression, usually accompanied by fatigue.

4. Fatigue and weakness
Persistent fatigue affects daily life, manifesting as poor energy and reduced physical strength.

5. Respiratory symptoms
Enlarged chest lymph nodes can cause shortness of breath, coughing, and chest pain, and in severe cases, impair respiratory function.

6. Abdominal pain and bloating
Enlargement of abdominal lymph nodes or spleen leads to abdominal discomfort and bloating.

7. Skin itching
Some patients suffer from generalized itching, severely impacting quality of life.

8. Bleeding tendency
Bone marrow involvement can cause thrombocytopenia, leading to skin bruising and nosebleeds.

Conclusion

Lymphoma, as a complex and serious malignant tumor, requires early recognition and timely treatment. Experts at United Life International Medical Center emphasize that combining modern immune reconstruction cell therapy with comprehensive multidisciplinary strategies can significantly improve survival rates and quality of life. Both patients and healthcare providers should stay vigilant for early detection and treatment, offering more hope for recovery to lymphoma patients.