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Rheumatoid Arthritis Overview

Rheumatoid arthritis is a chronic inflammatory disease of unknown etiology that primarily affects joints and surrounding tissues. It often presents symmetrically, accompanied by morning stiffness and restricted mobility. Without timely intervention, it can lead to irreversible joint destruction and disability, causing long-term impacts on patients’ lives and mental health.

Global Incidence

1. Europe and North America

The prevalence of rheumatoid arthritis in Europe and North America is about 0.5% to 1% of the population, with significantly more female patients than male. Well-established healthcare systems enable earlier diagnosis and standardized treatment in most cases, but challenges remain in treating elderly patients and those with multiple comorbidities.

2. Southeast Asia

The prevalence of rheumatoid arthritis in Southeast Asia is about 0.2% to 0.6%. In some rural and remote areas, delayed medical consultation is common. Climate, dietary habits, and life stress are considered closely related to the development and progression of the disease.

Main Harms

1. Joint structure destruction

Long-term inflammation gradually damages cartilage and bone, leading to mobility impairment and joint deformity. Some patients may develop significant functional loss within a few years, affecting daily life and work ability, sometimes requiring assistance for basic care.

2. Systemic damage

Rheumatoid arthritis affects not only the joints but may also involve the heart, lungs, and blood vessels, causing complications such as cardiovascular disease and pulmonary fibrosis. These extra-articular damages often increase mortality risk and add to the overall disease burden.

Emerging Treatment Methods

Immune Reconstruction Cell Therapy

Immune reconstruction cell therapy works by supplementing and reinfusing immune cells with normal function to rebuild immune balance, suppress abnormal inflammatory responses, repair damaged joint tissues, and reduce disease recurrence. This therapy can target lesions precisely, minimize long-term drug side effects, and has shown potential in clinical applications for improving quality of life and slowing joint damage.

1. Precision immune regulation

Cell therapy can specifically suppress pathological immune responses, reducing collateral damage to healthy tissues, and helping patients achieve more stable disease control.

2. Tissue function repair

By promoting cartilage repair and improving the joint environment, cell therapy helps slow structural damage and enhances joint mobility.

3. Reduced relapse frequency

Cell therapy may reduce the frequency of flare-ups, allowing patients to enjoy longer remission periods and overall improved quality of life.

In actual treatment, patients undergoing traditional therapies often face immune dysfunction, increased infection risk, and slow recovery. To better support patients, enhance treatment tolerance, and improve quality of life, phased immune reconstruction plans tailored to different treatment cycles are required.

● Short-term plan: Rapidly boost immunity through immune cell reinfusion to strengthen treatment effects.

● Mid-term plan: Reduce side effects of conventional therapies, promote recovery, and ensure completion of standardized regimens.

● Long-term plan: Gradually enhance immunity through immune cell reconstruction, gut immune reconstruction, elemental immune reconstruction, and immune nutrition reconstruction, ultimately improving quality of life and extending survival.

Conventional Treatment Methods

1. Nonsteroidal anti-inflammatory drugs (NSAIDs)

These relieve joint pain and inflammation, suitable for mild to moderate patients, but long-term use requires caution due to gastrointestinal and cardiovascular side effects.

2. Disease-modifying antirheumatic drugs (DMARDs)

Drugs such as methotrexate and leflunomide can slow disease progression and form the cornerstone of treatment.

3. Biologics

Designed to target specific inflammatory pathways, such as TNF-α inhibitors, these drugs can significantly improve symptoms and quality of life.

4. Glucocorticoids

Short-term use can quickly control inflammation, but side effects such as osteoporosis and diabetes must be closely monitored.

5. Physical therapy and rehabilitation

Including joint function training, heat therapy, and physiotherapy to help maintain mobility and reduce pain.

Conclusion

Rheumatoid arthritis is a chronic, recurrent, and highly disabling disease that not only threatens joint function but may also endanger multiple systems. Early scientific intervention and continuous management are essential to reduce disability rates. Experts at United Life International Medical Center emphasize that combining conventional and emerging therapies offers hope for long-term disease control and improved quality of life.