Diagnosis of Chronic Nephritis

Chronic nephritis is a disease caused by long-term chronic inflammation of the glomeruli. Without timely diagnosis and treatment, it may progress to chronic renal failure. Early diagnosis helps effectively control the disease and prevent renal function deterioration. Diagnosis mainly involves urine analysis, blood tests, and renal imaging examinations, and renal biopsy may be required to determine the pathological type.

Diagnostic Basis of Chronic Nephritis

1. Clinical Manifestation Analysis
Patients with chronic nephritis often present with abnormal urine such as proteinuria or hematuria, accompanied by edema and hypertension. Although clinical symptoms are non-specific, they provide important clues and must be combined with other test results for comprehensive judgment.

2. Urine Examination
Routine urinalysis is the foundation of diagnosis. The presence of proteinuria, hematuria, and casts indicates glomerular damage. Urine sediment analysis can reveal red blood cells, white blood cells, and casts, which help determine the type and activity of inflammation.

3. Blood Tests
Serum creatinine and urea nitrogen reflect renal excretory function. Changes in serum complement levels and immunoglobulins indicate immune mechanisms, assisting in disease assessment and treatment guidance.

4. Imaging Examinations
Renal ultrasound can evaluate kidney size, morphology, and blood flow, detect parenchymal damage, and exclude other renal diseases, aiding in diagnosis and monitoring.

5. Renal Biopsy
Renal biopsy is the gold standard for diagnosing chronic nephritis. Pathological examination confirms the type of inflammation, severity of lesions, and degree of fibrosis, providing important guidance for treatment planning.

6. Immunological Tests
Testing for autoantibodies such as ANA and anti-GBM antibodies helps rule out or confirm autoimmune nephritis, further clarifying the cause.

7. Other Auxiliary Examinations
Blood pressure monitoring, 24-hour urinary protein quantification, and electrolyte testing comprehensively reflect disease activity and complication risks, assisting in overall treatment evaluation.

Conclusion

The diagnosis of chronic nephritis depends on comprehensive analysis of multiple test results. Early and accurate diagnosis is crucial to controlling the disease and delaying renal function deterioration. Experts from United Life International Medical Center remind patients to undergo regular comprehensive check-ups and adopt advanced technologies such as stem cell therapy for scientific and standardized disease management, improving quality of life and reducing complication risks.