Soft tissue tumors are tumors that originate from non-epithelial tissues such as muscle, fat, blood vessels, nerve sheaths, or fascia, including both benign lesions and malignant soft tissue sarcomas with invasive and metastatic potential. These tumors often arise insidiously, with atypical early symptoms, making them easily overlooked by patients. In most cases, tumors are only detected when painless masses gradually enlarge. Due to their wide growth sites and numerous subtypes, diagnosis and treatment face significant challenges.
Soft tissue tumors occur worldwide. Incidence rates are relatively stable in Europe and the U.S., but numbers are rising annually in the Asia-Pacific region, particularly in China, Japan, and South Korea, with higher proportions of malignancy in some areas. With the popularization of imaging techniques and pathology, more early-stage cases are being detected in time.
1. Local functional damage
Malignant soft tissue tumors have strong local invasiveness, which can compress or destroy adjacent nerves, blood vessels, and organ tissues, leading to pain, restricted movement, limb numbness, and other functional impairments.
2. Prone to recurrence and metastasis
Although surgically removed, some tumor types have a high recurrence tendency and may metastasize through blood or lymphatic pathways to the lungs, bones, liver, and other areas, increasing treatment difficulty.
3. Complex pathological types
Soft tissue tumors have over 50 subtypes, with significant differences in biological behavior and treatment response. Inaccurate classification may lead to erroneous treatment strategies.
4. Psychological and quality of life impact
Some tumors occur in the limbs or face, and treatment may require removal of critical tissues, resulting in limb defects or appearance changes, placing psychological pressure on patients and affecting daily life and social interactions.
Immune reconstruction cell therapy activates and reconstructs the body’s immune defense to recognize and clear residual or metastatic tumor cells, showing positive effects in preventing recurrence and prolonging tumor-free survival. For patients with high recurrence and high metastasis risk, combining this therapy after surgery has become an important part of international comprehensive tumor treatment.
During traditional treatments such as surgery, radiotherapy, and chemotherapy, tumor patients often face immune dysfunction, increased infection risk, and slow recovery. To help patients better sustain treatment, improve tolerance, and enhance quality of life, phased immune reconstruction plans tailored to different treatment cycles should be scientifically developed.
● Short-term plan: Rapidly enhance immunity through immune cell reinfusion, boosting the effectiveness of anti-tumor treatment.
● Mid-term plan: Reduce the side effects of traditional treatments, promote physical recovery, and complete standardized treatment courses.
● Long-term plan: Enhance overall immunity through immune cell reconstruction, gut immune reconstruction, elemental immune reconstruction, and immune nutrition reconstruction, thereby improving quality of life and prolonging survival.
1. Surgical resection as the core treatment
Most soft tissue tumors are primarily treated with surgical resection. For well-defined lesions without metastasis, complete excision can achieve long-term control. Surgical approaches depend on tumor location, size, and its relation to critical structures.
2. Radiotherapy to improve local control rate
Postoperative radiotherapy is often used for positive margins or high-grade tumors to clear residual microscopic cells and reduce recurrence rates. For inoperable tumors, radiotherapy may also be considered as a palliative measure.
3. Chemotherapy as an adjunct strategy
Some highly malignant sarcoma types (such as synovial sarcoma and Ewing’s sarcoma) are sensitive to chemotherapy, which can shrink tumors preoperatively or prevent metastasis postoperatively. Common drugs include doxorubicin, ifosfamide, and others.
4. Attempts at minimally invasive treatments
For some well-defined, small-volume tumors, minimally invasive techniques such as radiofrequency ablation and cryotherapy may be attempted. These approaches reduce tissue damage and accelerate postoperative recovery, suitable for elderly or surgery-intolerant patients.
Soft tissue tumors have high local invasiveness and metastatic potential, requiring early detection, early diagnosis, and comprehensive treatment. Experts at United Life International Medical Center emphasize that integrating multimodal approaches such as immune reconstruction cell therapy can enhance therapeutic effects and extend patient survival.